Chromosome Mapping in Eukaryotes
if they are on different
if they are on the same
Genes on the same chromosome would
between nonsister chromatids occurs during meiosis.
to each other on the same chromosome are
occur between them.
frequencies between linked genes provide an estimate of the
(interlocus distance) and can be used to construct a chromosome
The percentage of
involved in an exchange between two genes is
the percentage of recombinant gametes
(SCO) alters linkage between two genes only if the crossover occurs
those two genes.
(DCOs) can be used to determine the order of
genes on the chromosome.
technique can be used to map three
genes in one
As the distance between linked genes increases, the mapping
due to undetected multiple crossovers that can be predicted by a
The large numbers of mutants in
has allowed extensive chromosome
in this and other organisms such as maize and mice.
Mapping in maize using
markers established that crossing over involves a
of chromosome regions.
, homologs can pair up during
, allowing mitotic
to take place.
Agents that induce chromosome
increase the frequency of sister
but do not produce recombination.
, meiosis produces eight
, allowing ordered
can be used for
in which a specific gene product can be correlated with a