Gene Mutation, DNA Repair, and Transposition
in DNA sequence and can occur
by an external agent (mutagen).
in nucleotides can result in
mutations due to anomalous base
can also lead to mutation.
Other chemical mutagens include
which donate an alkyl group to nucleotides.
In general, base
can lead to
mutations during DNA
between purines and pyrimidines.
rays are also
sequences can cause several human genetic disorders.
test uses bacteria selected for their sensitivity to specific types of mutagenesis to screen compounds for potential
can restore gaps created during DNA
due to damaged nucleotides.
in prokaryotes can remove thymine dimers caused by UV light.
Two types of excision repair can also repair damaged DNA:
(transposons or "jumping genes") can move within the
(Activator) elements contain a
similar to that of