Bio3400 Chapter 16 Regulation of Gene Expression in Prokaryotes
  1. Prokaryotes respond to environmental conditions by regulating transcription via            ,               , or              control.
  2. In E. coli, lactose metabolism is regulated by           control of an            system, where          is the inducer.

    • Expression of the lac operon is also subject to positive control: the operon is             by the catabolite-activating protein (CAP), together with Cyclic adenosine monophosphate ( cAMP ) when          is absent.

    • Binding of the repressor to the           forms a             loop in the lac operon DNA.

  3. The E. coli tryptophan (trp) operon is a              system that is repressed by              of the transcript.

    • Bacillus subtilis uses a combination of       and AT proteins to regulate its trp operon via              .

  4. The arabinose (a monosaccharide) operon is subject to both positive and negative regulation by the       protein.