Translation initiation.
- The small ribosomal subunit binds to several initiation factors (IF1, 2, 3);
this complex binds to mRNA.
- Initiator tRNAfmet binds to mRNA
AUG codon in the
P
(peptidyl) site
GTP is hydrolyzed to provide energy for the reactions.
-
Large subunit binds to complex. Elongation factor Tu binds to the next tRNA,
facilitating entry into the
A
(aminoacyl) site.